Segregation Analysis for Variant Interpretation

An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) , and further popularised by Bayrak-Toydemir et al. (2008) . This implementation allows custom penetrance values and liability classes, and includes specialised pedigree visualisations.


Reference manual

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0.2.0 by Magnus Dehli Vigeland, 8 months ago

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Authors: Magnus Dehli Vigeland [aut, cre]

Documentation:   PDF Manual  

GPL-3 license

Imports pedprobr

Depends on pedtools

Suggests testthat

Imported by pedsuite.

See at CRAN