Segregation Analysis for Variant Interpretation

An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) , and further popularised by Bayrak-Toydemir et al. (2008) . This implementation allows custom penetrance values and liability classes, and includes specialised pedigree visualisations.


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install.packages("segregatr")

0.2.0 by Magnus Dehli Vigeland, 8 months ago


https://github.com/magnusdv/segregatr


Report a bug at https://github.com/magnusdv/segregatr/issues


Browse source code at https://github.com/cran/segregatr


Authors: Magnus Dehli Vigeland [aut, cre]


Documentation:   PDF Manual  


GPL-3 license


Imports pedprobr

Depends on pedtools

Suggests testthat


Imported by pedsuite.


See at CRAN