Pharmacokinetics in R

Conduct a noncompartmental analysis as closely as possible to the most widely used commercial software. The core noncompartmental computations are delegated to the 'NonCompart' package so that the two share a single, maintained engine. Some features are 1) CDISC SDTM terms 2) Automatic slope selection with the same criterion of WinNonlin(R), restricted by default to samples after the end of an infusion 3) Supporting both 'linear-up linear-down' and 'linear-up log-down' method 4) Interval(partial) AUCs with 'linear' or 'log' interpolation method * Reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107).


Reference manual

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install.packages("pkr")

0.1.6 by Kyun-Seop Bae, 3 months ago


https://cran.r-project.org/package=pkr


Browse source code at https://github.com/cran/pkr


Authors: Kyun-Seop Bae [aut, cre] , Jee Eun Lee [aut]


Documentation:   PDF Manual  


GPL-3 license


Imports NonCompart, foreign, grDevices, graphics, grid, stats, utils

Suggests binr, forestplot, rtf


See at CRAN