Variable Selection in PH Cure Model with Time-Varying Covariates

Implementation of the semi-parametric proportional-hazards (PH) of Sy and Taylor (2000) extended to time-varying covariates. Estimation and variable selection are based on the methodology described in Beretta and Heuchenne (2019) ; confidence intervals of the parameter estimates may be computed using a bootstrap approach. Moreover, data following the PH cure model may be simulated using a method similar to Hendry (2014) , where the event-times are generated on a continuous scale from a piecewise exponential distribution conditional on time-varying covariates.


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1.0.2 by Alessandro Beretta, a year ago

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Authors: Alessandro Beretta [aut, cre] , C├ędric Heuchenne [aut]

Documentation:   PDF Manual  

GPL-2 | GPL-3 license

Imports Rcpp, MASS, Rdpack

Depends on survival

Linking to Rcpp, RcppArmadillo

See at CRAN