Protein Binding Models

Binding models which are useful when analysing protein-ligand interactions by techniques such as Biolayer Interferometry (BLI) or Surface Plasmon Resonance (SPR). Naman B. Shah, Thomas M. Duncan (2014) . Hoang H. Nguyen et al. (2015) . After initial binding parameters are known, binding curves can be simulated and parameters can be varied. The models within this package may also be used to fit a curve to measured binding data using non-linear regression.


News

Version 1.1.0

  • Added baseline drift parameter
  • Added global offset parameter
  • Added dissociation offset parameter

Version 1.0.0

  • First version.

Reference manual

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install.packages("pbm")

1.1.0 by Jonathan Davies, a year ago


https://github.com/jonathanrd/pbm


Report a bug at https://github.com/jonathanrd/pbm/issues


Browse source code at https://github.com/cran/pbm


Authors: Jonathan Davies [aut, cre]


Documentation:   PDF Manual  


MIT + file LICENSE license


Suggests testthat, knitr, rmarkdown


See at CRAN