Optimal Row-Column Designs for Two-Colour cDNA Microarray Experiments

Computes A-, MV-, D- and E-optimal or near-optimal row-column designs for two-colour cDNA microarray experiments using the linear fixed effects and mixed effects models where the interest is in a comparison of all pairwise treatment contrasts. The algorithms used in this package are based on the array exchange and treatment exchange algorithms adopted from Debusho, Gemechu and Haines (2016, unpublished) algorithms after adjusting for the row-column designs setup. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.


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install.packages("optrcdmaeAT")

1.0.0 by Dibaba Bayisa Gemechu, 2 years ago


Browse source code at https://github.com/cran/optrcdmaeAT


Authors: Legesse Kassa Debusho , Dibaba Bayisa Gemechu , and Linda Haines


Documentation:   PDF Manual  


Task views: Design of Experiments (DoE) & Analysis of Experimental Data


GPL-2 license


Depends on MASS, Matrix, igraph, tcltk


See at CRAN