Gene set analysis based on GSZ-scoring function and asymptotic p-value

Performs gene set analysis based on GSZ scoring function and asymptotic p-value. It is different from GSZ in that it implements asymptotic p-values instead of empirical p-values. Asymptotic p-values are calculated by fitting suitable distribution model to the null distribution. Unlike empirical p-values, resolution of asymptotic p-values are independent of the number of permutations and hence requires considerably fewer permutations. In addition, this package allows gene set analysis with seven other popular gene set analysis methods.


Reference manual

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1.0 by Pashupati Mishra, 8 years ago

Browse source code at

Authors: Pashupati Mishra , Petri Toronen

Documentation:   PDF Manual  

GPL (>= 2) license

Depends on Biobase, GSA, limma, MASS, ismev

See at CRAN