Lan-DeMets Method for Group Sequential Boundaries

Computations related to group sequential boundaries. Includes calculation of bounds using the Lan-DeMets alpha spending function approach.


Reference manual

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1.1-1.1 by Charlie Casper, 3 years ago

Browse source code at

Authors: Charlie Casper and Oscar A. Perez. Based on FORTRAN program ld98.

Documentation:   PDF Manual  

Task views: Clinical Trial Design, Monitoring, and Analysis

GPL (>= 2) license

Imports lattice

Imported by AGSDest, SurvGSD, blockRAR, gsrsb, triggerstrategy.

See at CRAN