Group Sequential Designs of Multi-Arm Multi-Stage Trials

It provides functions to generate operating characteristics and to calculate Sequential Conditional Probability Ratio Tests(SCPRT) efficacy and futility boundary values along with sample/event size of Multi-Arm Multi-Stage(MAMS) trials for different outcomes. The package is based on Jianrong Wu, Yimei Li, Liang Zhu (2023) , Jianrong Wu, Yimei Li (2023) "Group Sequential Multi-Arm Multi-Stage Survival Trial Design with Treatment Selection"(Manuscript accepted for publication) and Jianrong Wu, Yimei Li, Shengping Yang (2023) "Group Sequential Multi-Arm Multi-Stage Trial Design with Ordinal Endpoints"(In preparation).


Reference manual

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install.packages("gsMAMS")

0.7.2 by Tushar Patni, 2 years ago


https://github.com/Tpatni719/gsMAMS


Report a bug at https://github.com/Tpatni719/gsMAMS/issues


Browse source code at https://github.com/cran/gsMAMS


Authors: Tushar Patni [aut, cre] , Yimei Li [aut] , Jianrong Wu [aut]


Documentation:   PDF Manual  


GPL-3 license


Imports mvtnorm, stats, survival

Suggests knitr, rmarkdown, testthat


See at CRAN