Design and Analysis of 2x2 Factorial Trial

Used for the design and analysis of a 2x2 factorial trial for a time-to-event endpoint. Performs power calculations and significance testing. Important reference papers include Slud EV. (1994) < https://www.ncbi.nlm.nih.gov/pubmed/8086609> Lin DY, Gong J, Gallo P, Bunn PH, Couper D. (2016) Leifer ES, Troendle JF, Kolecki A, Follmann DA. (2019) < https://github.com/EricSLeifer/factorial2x2/blob/master/Leifer%20et%20al%20Factorial.pdf>.


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Reference manual

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install.packages("factorial2x2")

0.1.0 by Eric Leifer, 3 months ago


Browse source code at https://github.com/cran/factorial2x2


Authors: Eric Leifer and James Troendle


Documentation:   PDF Manual  


GPL-2 license


Depends on survival, stats, mvtnorm

Suggests knitr, rmarkdown


See at CRAN