Multi-Context Colocalization Analysis for QTL and GWAS Studies

A multi-task learning approach to variable selection regression with highly correlated predictors and sparse effects, based on frequentist statistical inference. It provides statistical evidence to identify which subsets of predictors have non-zero effects on which subsets of response variables, motivated and designed for colocalization analysis across genome-wide association studies (GWAS) and quantitative trait loci (QTL) studies. The ColocBoost model is described in Cao et. al. (2025) .


Reference manual

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install.packages("colocboost")

1.0.10 by Xuewei Cao, a month ago


https://github.com/StatFunGen/colocboost


Report a bug at https://github.com/StatFunGen/colocboost/issues


Browse source code at https://github.com/cran/colocboost


Authors: Xuewei Cao [cre, aut, cph] , Haochen Sun [aut, cph] , Ru Feng [aut, cph] , Daniel Nachun [aut, cph] , Kushal Dey [aut, cph] , Gao Wang [aut, cph]


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports Rfast, matrixStats

Suggests testthat, knitr, rmarkdown, ashr, MASS, susieR


See at CRAN