Removes the Cell-Cycle Effect from Single-Cell RNA-Sequencing Data

Implements a method for identifying and removing the cell-cycle effect from scRNA-Seq data. The description of the method is in Barron M. and Li J. (2016) . Identifying and removing the cell-cycle effect from single-cell RNA-Sequencing data. Submitted. Different from previous methods, ccRemover implements a mechanism that formally tests whether a component is cell-cycle related or not, and thus while it often thoroughly removes the cell-cycle effect, it preserves other features/signals of interest in the data.


Reference manual

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1.0.4 by Jun Li, 4 years ago

Browse source code at

Authors: Jun Li [aut, cre] , Martin Barron [aut]

Documentation:   PDF Manual  

GPL-3 license

Imports stats, utils

Suggests knitr, rmarkdown

See at CRAN