Covariate-Adaptive Randomization for Clinical Trials

Provides functions and command-line user interface to generate allocation sequence by covariate-adaptive randomization for clinical trials. The package currently supports six covariate-adaptive randomization procedures. Three hypothesis testing methods that are valid and robust under covariate-adaptive randomization are also available in the package to facilitate the inference for treatment effect under the included randomization procedures. Additionally, the package provides comprehensive and efficient tools to allow one to evaluate and compare the performance of randomization procedures and tests based on various criteria.


Reference manual

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1.1 by Xiaoqing Ye, 2 months ago

Browse source code at

Authors: Fuyi Tu [aut] , Xiaoqing Ye [aut, cre] , Wei Ma [aut, ths] , Feifang Hu [aut, ths]

Documentation:   PDF Manual  

GPL (>= 2) license

Imports Rcpp, ggplot2, gridExtra, stringr

Suggests dplyr

Linking to Rcpp, RcppArmadillo

See at CRAN