Blinded Sample Size Recalculation

Computation of key characteristics and plots for blinded sample size recalculation. Continuous as well as binary endpoints are supported in superiority and non-inferiority trials. The implemented methods include the approaches by Lu, K. (2019) , Kieser, M. and Friede, T. (2000) , Friede, T. and Kieser, M. (2004) , Friede, T., Mitchell, C., Mueller-Veltern, G. (2007) , and Friede, T. and Kieser, M. (2011) .


Reference manual

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0.1.3 by Lukas Baumann, 7 months ago

Browse source code at

Authors: Lukas Baumann [aut, cre] , Maximilian Pilz [aut] , Institute of Medical Biometry and Informatics - University of Heidelberg [cph]

Documentation:   PDF Manual  

MIT + file LICENSE license

Imports methods, Rcpp

Suggests testthat, covr

Linking to Rcpp

See at CRAN