Simulate Survival Data for Randomized Clinical Trials

A system to simulate clinical trials with time to event endpoints. Event simulation is based on Cox models allowing for covariates in addition to the treatment or group factor. Specific drop-out rates (separate from administrative censoring) can be controlled in the simulation. Other features include stratified randomization, non-proportional hazards, different accrual patterns, and event projection (timing to reach the target event) based on interim data.


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Reference manual

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install.packages("TwoArmSurvSim")

0.1 by Bo Zhang, a month ago


Browse source code at https://github.com/cran/TwoArmSurvSim


Authors: Bo Zhang [cre, aut] , Yi Zhong [aut, ctb] , Ginny Peng [aut, ctb] , Bin Yao [aut, ctb]


Documentation:   PDF Manual  


GPL (>= 2) license


Depends on blockrand, dplyr, survival


See at CRAN