Optimal Two and Three Stage Designs for Single-Arm and Two-Arm Randomized Controlled Trials with a Long-Term Binary Endpoint

Optimal two and three stage designs monitoring time-to-event endpoints at a specified timepoint


Reference manual

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3.0.1 by Bo Huang, 9 years ago

Browse source code at https://github.com/cran/OptInterim

Authors: Bo Huang <[email protected].com> and Neal Thomas <[email protected]>

Documentation:   PDF Manual  

Task views: Design of Experiments (DoE) & Analysis of Experimental Data

GPL (>= 2) license

Depends on mvtnorm, clinfun, stats, graphics

See at CRAN