Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions

Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) and Kiihl et al. (2018, to appear).


Reference manual

It appears you don't have a PDF plugin for this browser. You can click here to download the reference manual.


0.3.1 by Samara Kiihl, 3 months ago

Report a bug at

Browse source code at

Authors: Samara Kiihl [aut, cre] , Maria Jose Martinez-Garrido [aut] , Arce Domingo-Relloso [aut] , Jose Bermudez [aut] , Maria Tellez-Plaza [aut]

Documentation:   PDF Manual  

MIT + file LICENSE license

Suggests minfi, microbenchmark, GEOquery, knitr, BiocStyle, rmarkdown, IlluminaHumanMethylation450kmanifest

See at CRAN