Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions

Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) and Kiihl et al. (2019) .


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install.packages("MLML2R")

0.3.2 by Samara Kiihl, 3 months ago


https://github.com/samarafk/MLML2R


Report a bug at https://github.com/samarafk/MLML2R/issues


Browse source code at https://github.com/cran/MLML2R


Authors: Samara Kiihl [aut, cre] , Maria Jose Martinez-Garrido [aut] , Arce Domingo-Relloso [aut] , Jose Bermudez [aut] , Maria Tellez-Plaza [aut]


Documentation:   PDF Manual  


MIT + file LICENSE license


Suggests minfi, microbenchmark, GEOquery, knitr, BiocStyle, rmarkdown, IlluminaHumanMethylation450kmanifest


See at CRAN