LUCID with Multiple Omics Data

Implements Latent Unknown Clusters By Integrating Multi-omics Data (LUCID; Peng (2019) ) for integrative clustering with exposures, multi-omics data, and health outcomes. Supports three integration strategies: early, parallel, and serial. Provides model fitting and tuning, lasso-type regularization for exposure and omics feature selection, handling of missing data, including both sporadic and complete-case patterns, prediction, and g-computation for estimating causal effects of exposures, bootstrap inference for uncertainty estimation, and S3 summary and plot methods. For the multi-omics integration framework, see Jia (2024) < https://journal.r-project.org/articles/RJ-2024-012/RJ-2024-012.pdf>. For the missing-data imputation mechanism, see Jia (2024) .


Reference manual

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install.packages("LUCIDus")

3.2.1 by Qiran Jia, 2 months ago


https://journal.r-project.org/articles/RJ-2024-012/RJ-2024-012.pdf, https://doi.org/10.1093/bioadv/vbae123


Browse source code at https://github.com/cran/LUCIDus


Authors: Qiran Jia [aut, cre] , Yinqi Zhao [aut] , David Conti [ths] , Jesse Goodrich [ctb]


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports mclust, nnet, boot, jsonlite, networkD3, progress, stats, utils, glasso, glmnet, ggplot2, grDevices

Suggests testthat, knitr, rmarkdown, plotly, mix, visdat


Suggested by MosaiClusteR.


See at CRAN