Gene-Based Segregation Test

Implements the gene-based segregation test(GESE) and the weighted GESE test for identifying genes with causal variants of large effects for family-based sequencing data. The methods are described in Qiao, D. Lange, C., Laird, N.M., Won, S., Hobbs, B., et al. 2016. Gene-based segregation method for identifying rare variants for family-based sequencing studies. More details can be found at <>.


Reference manual

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2.0.0 by Dandi Qiao, 5 months ago

Browse source code at

Authors: Dandi Qiao, Michael H. Cho

Documentation:   PDF Manual  

GPL-2 license

Depends on kinship2

Suggests knitr, rmarkdown

See at CRAN