Gene-Based Segregation Test

Implements the gene-based segregation test(GESE) and the weighted GESE test for identifying genes with causal variants of large effects for family-based sequencing data. The methods are described in Qiao, D. Lange, C., Laird, N.M., Won, S., Hersh, C.P., et al. (2017). . Gene-based segregation method for identifying rare variants for family-based sequencing studies. Genet Epidemiol 41(4):309-319. More details can be found at <>.


Reference manual

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2.0.1 by Dandi Qiao, 4 years ago

Browse source code at

Authors: Dandi Qiao , Michael H. Cho

Documentation:   PDF Manual  

GPL-2 license

Depends on kinship2

Suggests knitr, rmarkdown

See at CRAN