Analyzing Human Exposure to Mosquito Biting

Tools to analyse human and mosquito behavioral interactions and to compute exposure to mosquito bites estimates. Using behavioral data for human individuals and biting patterns for mosquitoes, you will be able to compute hourly exposure for bed net users and non-users, and summarize (e.g. proportion indoors and outdoors, proportion per time periods, and proportion prevented by bed nets) or visualize these dynamics across a 24-hour cycle.

ExpBites: Analyze Human Exposure to Mosquito Bites

Overview

ExpBites is an R package to compute mosquito biting exposure based on hourly human and mosquito behavior. It is designed for entomological modeling and malaria vector control analysis, particularly in the context of insecticide-treated net (ITN) usage.

Features

Simulate individual human behavior (outdoors, indoors awake, asleep, under bed net) over 24-hour cycles (for test purpose).
Simulate mosquito biting activity indoors and outdoors (for test purpose).
Estimate exposure to mosquito bites for bednet users and non-users.
Calculate proportions of exposure prevented by nets.
Calculate proportions of exposure indoors or during specified time intervals.
Visualize exposure and behavior patterns over time.

Installation

You can install the development version of ExpBites from GitHub:

# install.packages("devtools")
devtools::install_github("Nmoiroux/ExpBites")

Make sure you have the required dependencies:

install.packages(c("dplyr", "tidyr", "ggplot2", "Rdpack"))

Example

library(ExpBites) 

# Generate simulated human and mosquito data (for test purpose)
df <- gen_df_human(n_individuals = 100) 
df_bites <- gen_df_mosquito() 

# Calculate hourly exposure to mosquito bites 
exp_result <- calculate_Exp(df, df_bites) 

# Summarize exposure for entire day and a specific time window (e.g., 22h to 5h) 
summary_tbl <- summarise_exposure(exp_result, interval = c(22, 5))

print(summary_tbl) 

# Plot exposure patterns 
plot_exposure(exp_result) 

# Plot mosquito and human behavior patterns 
plot_behaviors(exp_result)

References

This package builds upon and extends the models described in:

Killeen et al. (2006). Quantifying behavioural interactions between humans and mosquitoes... BMC Infectious Diseases
Geissbühler et al. (2007). Interdependence of domestic malaria prevention measures... Malaria Journal
Moiroux et al. (2014). Human exposure to early morning Anopheles biting... PLoS One