Decomposition of Bulk Expression with Single-Cell Sequencing

Provides tools to accurately estimate cell type abundances from heterogeneous bulk expression. A reference-based method utilizes single-cell information to generate a signature matrix and transformation of bulk expression for accurate regression based estimates. A marker-based method utilizes known cell-specific marker genes to measure relative abundances across samples. For more details, see Jew and Alvarez et al (2019) .


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install.packages("BisqueRNA")

1.0 by Brandon Jew, 6 months ago


https://www.biorxiv.org/content/10.1101/669911v1


Report a bug at https://github.com/cozygene/bisque/issues


Browse source code at https://github.com/cran/BisqueRNA


Authors: Brandon Jew [aut, cre] , Marcus Alvarez [aut]


Documentation:   PDF Manual  


GPL-3 license


Imports Biobase, lsei, methods, stats

Suggests Seurat, plyr, knitr, rmarkdown, testthat


See at CRAN