Bayesian Adaptive Designs for Phase II Trials with Binary Endpoint

Tools and workflow to choose design parameters in Bayesian adaptive single-arm phase II trial designs with binary endpoint (response, success) with possible stopping for efficacy and futility at interim analyses. Also contains routines to determine and visualize operating characteristics. See Kopp-Schneider et al. (2018) .

Bayesian adaptive designs for phase II trials with binary endpoint.


Reference manual

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0.1.3 by Manuel Wiesenfarth, 3 years ago

Browse source code at

Authors: Annette Kopp-Schneider , Manuel Wiesenfarth , Ulrich Abel

Documentation:   PDF Manual  

GPL-2 license

Depends on rmarkdown, shiny, shinyBS

Suggests knitr

See at CRAN