B Cell Receptor Somatic Hyper Mutation Analysis

Includes a set of functions to analyze for instance nucleotide frequencies as well as transition and transversion. Can reconstruct germline sequences based on the international ImMunoGeneTics information system (IMGT/HighV-QUEST) outputs, calculate and plot the difference (%) of nucleotides at 6 positions around a mutation to identify and characterize hotspot motifs as well as calculate and plot average mutation frequencies of nucleotide mutations resulting in amino acid substitution.


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install.packages("BCellMA")

0.3.4 by Olena Ohlei, 3 months ago


https://www.r-project.org


Browse source code at https://github.com/cran/BCellMA


Authors: Olena Ohlei <olena.ohlei@student.uni-luebeck.de>


Documentation:   PDF Manual  


GPL (>= 2) license


Depends on ggplot2, reshape2, grid

Suggests graphics, utils, knitr, rmarkdown


See at CRAN