B Cell Receptor Somatic Hyper Mutation Analysis

Includes a set of functions to analyze for instance nucleotide frequencies as well as transition and transversion. Can reconstruct germline sequences based on the international ImMunoGeneTics information system (IMGT/HighV-QUEST) outputs, calculate and plot the difference (%) of nucleotides at 6 positions around a mutation to identify and characterize hotspot motifs as well as calculate and plot average mutation frequencies of nucleotide mutations resulting in amino acid substitution.


Reference manual

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0.3.4 by Olena Ohlei, 5 years ago


Browse source code at https://github.com/cran/BCellMA

Authors: Olena Ohlei <[email protected]>

Documentation:   PDF Manual  

GPL (>= 2) license

Depends on ggplot2, reshape2, grid

Suggests graphics, utils, knitr, rmarkdown

See at CRAN