A package to simulate constrained phenotypes under a disease model H1

waffect (pronounced 'double-u affect' for 'weighted affectation') is a package to simulate phenotypic (case or control) datasets under a disease model H1 such that the total number of cases is constant across all the simulations (the constrain in the title). The package also makes it possible to generate phenotypes in the case of more than two classes, so that the number of phenotypes belonging to each class is constant across all the simulations. waffect is used to assess empirically the statistical power of Genome Wide Association studies.


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install.packages("waffect")

1.2 by G. Nuel, 7 years ago


Browse source code at https://github.com/cran/waffect


Authors: Gregory Nuel and Vittorio Perduca


Documentation:   PDF Manual  


GPL (>= 3) license


Depends on Rcpp

Suggests pROC

Linking to Rcpp


See at CRAN