DE Analysis for Single-Cell RNA-Sequencing Data

Implements the TWO-Component Single Cell Model-Based Association Method (TWO-SIGMA) for gene-level differential expression (DE) analysis and DE-based gene set testing of single-cell RNA-sequencing datasets. See Van Buren et al. (2020) and Van Buren et al. (2021) .


Reference manual

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1.0.2 by Eric Van Buren, a month ago

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Authors: Eric Van Buren [aut, cre] , Yun Li [aut] , Di Wu [aut] , Ming Hu [aut]

Documentation:   PDF Manual  

AGPL-3 license

Imports multcomp, glmmTMB, methods, pscl, pbapply, parallel, doParallel

Suggests testthat

See at CRAN