Cycle-Free Flux Balance Analysis (CycleFreeFlux)

Implement cycle-Free flux balance analysis (CycleFreeFlux), cycle-free flux variability, and Random Sampling of solution space. Desouki, A. A., Jarre, F., Gelius-Dietrich, G., & Lercher, M. J. (2015). CycleFreeFlux: efficient removal of thermodynamically infeasible loops from flux distributions. Bioinformatics, 31(13), 2159-2165. . Flux balance analysis is a technique to find fluxes in metabolic models at steady state. It is described in Orth, J.D., Thiele, I. and Palsson, B.O. What is flux balance analysis? Nat. Biotech. 28, 245-248 (2010).