Different techniques of cost constrained flux balance analysis.
1- MetabOlic Modeling with ENzyme kineTics 'MOMENT' which uses enzyme kinetic data and enzyme molecular
weights to constrain flux balance analysis(FBA) and it is described in Adadi, R., Volkmer, B., Milo, R.,
Heinemann, M., & Shlomi, T. (2012). Prediction of Microbial Growth Rate versus Biomass Yield by a Metabolic Network
with Kinetic Parameters, 8(7).
sybilccFBA Version History
Version 3.0.0 2018-11-11
Add function getccFBA_mat that gets the model of ccFBA as a matrix and includes protein complex stoichiometry.
Add function getGpr1iso that preprocesses the metabolic model to get for any catalysed reaction by set of isoenzymes the one iso enzyme (i.e the smallest Molecular Weight)
Add runFVA option to cfba_moment_mr to get flux variability.
Add parameter C_mu_coef that is used to have C as a linear function of mu (biomass) : C = RHS + C_mu_coef*Biomass.
Add function simulate_EColi to combine different functions and show a test case for them.
Add iML1515 data model
Add Kcat lists for EColi and molecular weight for iML1515 model
Version 2.0.0 2015-04-01
Version 1.0.0 2014-03-31