Estimating Infection Rates from Serological Data

Translates antibody levels measured in a (cross-sectional) population sample into an estimate of the frequency with which seroconversions (infections) occur in the sampled population.


seroincidence package


Antibody levels measured in a (cross–sectional) population sample can be translated into an estimate of the frequency with which seroconversions (infections) occur in the sampled population. Formulated simply: the presence of many high titres indicates that many subjects likely experienced infection recently, while low titres indicate a low frequency of infections in the sampled population.

The seroincidence calculator script was designed to use the longitudinal response characteristics by means of a set of parameters characterizing the longitudinal response of the selected serum antibodies.

Reference manual

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install.packages("seroincidence")

2.0.0 by Chantal Quinten, 8 years ago


https://ecdc.europa.eu/en/publications-data/seroincidence-calculator-tool


Browse source code at https://github.com/cran/seroincidence


Authors: Peter Teunis [aut] (Author of the method and original code.) , Jan van Eijkeren [aut] (Author of the method and original code.) , Daniel Lewandowski [com, ctb] (Creator of the R package.) , Chantal Quinten [cre, ctb] (Project manager and the package maintainer.)


Documentation:   PDF Manual  


GPL-3 license


Imports stats, utils

Suggests knitr, rmarkdown, parallel


See at CRAN