Copy Number Profiling using Sequencing and CBS

This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.


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install.packages("seqCBS")

1.2.1 by Jeremy J. Shen, 11 days ago


Browse source code at https://github.com/cran/seqCBS


Authors: Jeremy J. Shen , Nancy R. Zhang


Documentation:   PDF Manual  


GPL-2 license


Depends on clue


See at CRAN