Submission Confidence Index Engine

Converts standardized R4SUB (R for Regulatory Submission) evidence into indicator scores, pillar scores, and a Submission Confidence Index (SCI). Provides sensitivity analysis, explainability tables, and decision band classification to answer the question: are we ready for regulatory submission.


r4subscore

r4subscore is the scoring and calibration engine of the R4SUB ecosystem.

It converts standardized evidence (from r4subcore and companion packages like r4subtrace) into:

  • Indicator Scores (per-indicator 0--1)
  • Pillar Scores (per-domain 0--1)
  • Submission Confidence Index (SCI, 0--100)
  • Decision Bands (Ready / Minor Gaps / Conditional / High Risk)
  • Sensitivity Analysis (SCI stability under weight variations)
  • Explainability Tables (which indicators drive SCI up/down)

It answers the executive question:

Are we ready for regulatory submission -- and how confident are we?

Installation

pak::pak(c("R4SUB/r4subcore", "R4SUB/r4subscore"))

Quick Start

library(r4subcore)
library(r4subscore)

# assume ev is a validated evidence table
pillar_scores <- compute_pillar_scores(ev)
sci <- compute_sci(pillar_scores)

sci$SCI
sci$band

Core Functions

Function Purpose
sci_config_default() Pillar weights + decision bands config
classify_band() Classify an SCI value into a decision band
compute_indicator_scores() Severity-weighted indicator-level scores
compute_pillar_scores() Aggregate indicators into pillar scores
compute_sci() Compute SCI (0--100) + band classification
sci_sensitivity_analysis() SCI under alternative weight scenarios
sci_explain() Top loss contributors + pillar breakdown

SCI Bands

SCI Band Interpretation
85--100 ready Ready for Submission
70--84 minor_gaps Minor Gaps to Address
50--69 conditional Conditional -- Address Key Issues
0--49 high_risk High Risk

Scoring Logic

  1. Each evidence row gets a weighted score: result_score * (1 - severity_weight)
  2. Indicator scores = mean weighted score per indicator
  3. Pillar scores = mean indicator score per domain
  4. SCI = weighted sum of pillar scores x 100

License

MIT

Reference manual

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install.packages("r4subscore")

0.1.0 by Pawan Rama Mali, 7 months ago


https://github.com/R4SUB/r4subscore


Report a bug at https://github.com/R4SUB/r4subscore/issues


Browse source code at https://github.com/cran/r4subscore


Authors: Pawan Rama Mali [aut, cre, cph]


Documentation:   PDF Manual  


MIT + file LICENSE license


Imports cli, dplyr, r4subcore, rlang, tibble

Suggests testthat


Imported by r4sub.

Suggested by r4subpharma, r4subprofile.


See at CRAN