Candidate Gene Prioritization for Non-Communicable Diseases Based on Functional Information

In gene sequencing methods, the topological features of protein-protein interaction (PPI) networks are often used, such as ToppNet < https://toppgene.cchmc.org>. In this study, a candidate gene prioritization method was proposed for non-communicable diseases considering disease risks transferred between genes in weighted disease PPI networks with weights for nodes and edges based on functional information.


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install.packages("prioGene")

1.0.0 by Erqiang Hu, 12 days ago


Browse source code at https://github.com/cran/prioGene


Authors: Erqiang Hu [aut, cre]


Documentation:   PDF Manual  


Artistic-2.0 license


Imports AnnotationDbi, org.Hs.eg.db

Suggests knitr, rmarkdown, testthat


See at CRAN