Understanding Nonlinear Mixed Effects Modeling for Population Pharmacokinetics

This shows how NONMEM(R) < http://www.iconplc.com/innovation/nonmem/> software works. NONMEM's classical estimation methods like 'First Order(FO) approximation', 'First Order Conditional Estimation(FOCE)', and 'Laplacian approximation' are explained.


Reference manual

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0.1.4 by Kyun-Seop Bae, 3 years ago


Browse source code at https://github.com/cran/nmw

Authors: Kyun-Seop Bae

Documentation:   PDF Manual  

Task views: Analysis of Pharmacokinetic Data

GPL-3 license

Depends on numDeriv

See at CRAN