Two Sample Mendelian Randomization using Robust Adjusted Profile Score

Mendelian randomization is a method of identifying and estimating a confounded causal effect using genetic instrumental variables. This packages implements methods for two-sample Mendelian randomization with summary statistics by using Robust Adjusted Profile Score (RAPS). References: Qingyuan Zhao, Jingshu Wang, Jack Bowden, Dylan S. Small. Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score. .


mr.raps is an R package for two-sample Mendelian randomization using the robust adjusted profile score. To install the package, run

library(devtools)
install_github("qingyuanzhao/mr.raps")

The main function is mr.raps. You can find examples by running

example(mr.raps)

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Reference manual

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install.packages("mr.raps")

0.2 by Qingyuan Zhao, 3 years ago


Browse source code at https://github.com/cran/mr.raps


Authors: Qingyuan Zhao [aut, cre]


Documentation:   PDF Manual  


GPL-3 license


Imports stats, graphics, nortest


See at CRAN