Two Sample Mendelian Randomization using Robust Adjusted Profile Score

Mendelian randomization is a method of identifying and estimating a confounded causal effect using genetic instrumental variables. This packages implements methods for two-sample Mendelian randomization with summary statistics by using Robust Adjusted Profile Score (RAPS). References: Qingyuan Zhao, Jingshu Wang, Jack Bowden, Dylan S. Small. Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score. .

mr.raps is an R package for two-sample Mendelian randomization using the robust adjusted profile score. To install the package, run


The main function is mr.raps. You can find examples by running



Reference manual

It appears you don't have a PDF plugin for this browser. You can click here to download the reference manual.


0.2 by Qingyuan Zhao, 4 years ago

Browse source code at

Authors: Qingyuan Zhao [aut, cre]

Documentation:   PDF Manual  

GPL-3 license

Imports stats, graphics, nortest

See at CRAN