Efficient Estimation of Grouped Survival Models Using the Exact Likelihood Function

These 'Rcpp'-based functions compute the efficient score statistics for grouped time-to-event data (Prentice and Gloeckler, 1978), with the optional inclusion of baseline covariates. Functions for estimating the parameter of interest and nuisance parameters, including baseline hazards, using maximum likelihood are also provided. A parallel set of functions allow for the incorporation of family structure of related individuals (e.g., trios). Note that the current implementation of the frailty model (Ripatti and Palmgren, 2000) is sensitive to departures from model assumptions, and should be considered experimental. For these data, the exact proportional-hazards-model-based likelihood is computed by evaluating multiple variable integration. The integration is accomplished using the 'Cuba' library (Hahn, 2005), and the source files are included in this package. The maximization process is carried out using Brent's algorithm, with the C++ code file from John Burkardt and John Denker (Brent, 2002).


groupedSurv v1.0.3 (Release date: 2018-06-28)

  • Revised package documentation and vignette

groupedSurv v1.0.2 (Release date: 2018-06-20)

  • Added support for matrix input
  • Added more examples of importing data from different sources to vignette
  • Fixed warning from GenABEL in vignette

groupedSurv v1.0.1 (Release date: 2018-05-15)

  • Fixed bugs causing errors on mac OSX and clang compiler
  • Revised package description

Reference manual

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1.0.3 by Jiaxing Lin, 7 months ago

Browse source code at https://github.com/cran/groupedSurv

Authors: Jiaxing Lin [aut] , Alexander Sibley [aut] , Tracy Truong [aut] , Kouros Owzar [aut] , Zhiguo Li [aut] , Yu Jiang [ctb] , Janice McCarthy [ctb] , Andrew Allen [ctb]

Documentation:   PDF Manual  

GPL (>= 2) license

Imports Rcpp, doParallel, doRNG, parallel, foreach, qvalue

Suggests knitr, snplist, BEDMatrix

Linking to Rcpp, RcppEigen, BH

See at CRAN