Phase I/II Adaptive Dose-Finding Design for Combination Studies

Phase I/II adaptive dose-finding design for combination studies where toxicity rates are supposed to increase with both agents.


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Reference manual

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install.packages("dfcomb")

3.0-0 by Jacques-Henri Jourdan, 9 months ago


Browse source code at https://github.com/cran/dfcomb


Authors: Marie-Karelle Riviere and Jacques-Henri Jourdan


Documentation:   PDF Manual  


Task views: Design of Experiments (DoE) & Analysis of Experimental Data


GPL-3 license


Linking to BH, Rcpp, RcppProgress


See at CRAN