Closed Testing with Globaltest for Pathway Analysis

A shortcut procedure is proposed to implement closed testing for large-scale multiple testings, especially with the global test. This shortcut is asymptotically equivalent to closed testing and post hoc. Users could detect any possible sets of features or pathways with family-wise error rate controlled. The global test is powerful to detect associations between a group of features and an outcome of interest.


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2.0 by Ningning Xu, 6 months ago

Browse source code at

Authors: Ningning Xu

Documentation:   PDF Manual  

GPL (>= 2) license

Imports Rcpp

Linking to Rcpp, BH

System requirements: C++11

Depended on by newFocus.

See at CRAN