Automated Covariate Selection Using HDPS Algorithm

Contains functions to implement automated covariate selection using methods described in the high-dimensional propensity score (HDPS) algorithm by Schneeweiss Covariate adjustment in real-world-observational-data (RWD) is important for for estimating adjusted outcomes and this can be done by using methods such as, but not limited to, propensity score matching, propensity score weighting and regression analysis. While these methods strive to statistically adjust for confounding, the major challenge is in selecting the potential covariates that can bias the outcomes comparison estimates in observational RWD (Real-World-Data). This is where the utility of automated covariate selection comes in. The functions in this package help to implement the three major steps of automated covariate selection as described by Schneeweiss et. al elsewhere. These three functions, in order of the steps required to execute automated covariate selection are, get_candidate_covariates(), get_recurrence_covariates() and get_prioritised_covariates(). In addition to these functions, a sample real-world-data from publicly available de-identified medical claims data is also available for running examples and also for further exploration. The original article where the algorithm is described by Schneeweiss (2009) .


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1.0.0 by Dennis Robert, a month ago

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Authors: Dennis Robert <[email protected]>

Documentation:   PDF Manual  

MIT + file LICENSE license

Imports purrr, data.table

Depends on dplyr

Suggests testthat

See at CRAN