Finding Multiple-Objective Optimal Designs for the 4-Parameter Logistic Model

Provide tools for finding multiple-objective optimal designs for estimating the shape of dose-response, the ED50 (the dose producing an effect midway between the expected responses at the extreme doses) and the MED (the minimum effective dose level) for the 2,3,4-parameter logistic models and for evaluating its efficiencies for the three objectives. The acronym VNM stands for V-algorithm using Newton Raphson method to search multiple-objective optimal design.


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Reference manual

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install.packages("VNM")

7.1 by Yarong Yang, 10 months ago


Browse source code at https://github.com/cran/VNM


Authors: Seung Won Hyun , Weng Kee Wong , and Yarong Yang


Documentation:   PDF Manual  


Task views: Design of Experiments (DoE) & Analysis of Experimental Data


GPL (>= 2) license


Imports graphics, Rcpp

Depends on methods

Linking to Rcpp


See at CRAN