Finding Multiple-Objective Optimal Designs for the 4-Parameter Logistic Model

Provide tools for finding multiple-objective optimal designs for estimating the shape of dose-response, the ED50 (the dose producing an effect midway between the expected responses at the extreme doses) and the MED (the minimum effective dose level) for the 2,3,4-parameter logistic models and for evaluating its efficiencies for the three objectives. The acronym VNM stands for V-algorithm using Newton Raphson method to search multiple-objective optimal design.


Reference manual

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7.1 by Yarong Yang, a year ago

Browse source code at

Authors: Seung Won Hyun , Weng Kee Wong , and Yarong Yang

Documentation:   PDF Manual  

Task views: Design of Experiments (DoE) & Analysis of Experimental Data

GPL (>= 2) license

Imports graphics, Rcpp

Depends on methods

Linking to Rcpp

See at CRAN