Transmission Ratio Distortion

Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.


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Reference manual

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install.packages("TRD")

1.1 by Lam Opal Huang, 5 years ago


Browse source code at https://github.com/cran/TRD


Authors: Lam Opal Huang


Documentation:   PDF Manual  


GPL (>= 2) license


Depends on Rlab


See at CRAN