Technical Variation Elimination with Ensemble Learning Architecture

The R implementation of TIGER. TIGER integrates random forest algorithm into an innovative ensemble learning architecture. Benefiting from this advanced architecture, TIGER is resilient to outliers, free from model tuning and less likely to be affected by specific hyperparameters. TIGER supports targeted and untargeted metabolomics data and is competent to perform both intra- and inter-batch technical variation removal. TIGER can also be used for cross-kit adjustment to ensure data obtained from different analytical assays can be effectively combined and compared. Reference: Han S. et al. (2022) .


Reference manual

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install.packages("TIGERr")

1.0.0 by Siyu Han, 5 years ago


Report a bug at https://github.com/HAN-Siyu/TIGER/issues


Browse source code at https://github.com/cran/TIGERr


Authors: Siyu Han [aut, cre] , Jialing Huang [aut] , Francesco Foppiano [aut] , Cornelia Prehn [aut] , Jerzy Adamski [aut] , Karsten Suhre [aut] , Ying Li [aut] , Giuseppe Matullo [aut] , Freimut Schliess [aut] , Christian Gieger [aut] , Annette Peters [aut] , Rui Wang-Sattler [aut]


Documentation:   PDF Manual  


GPL (>= 3) license


Imports parallel, pbapply, ppcor, randomForest, stats


See at CRAN