Knockoffs for Hidden Markov Models and Genetic Data

Generate knockoffs for genetic data and hidden Markov models. For more information, see the website below and the accompanying papers: "Gene hunting with hidden Markov model knockoffs", Sesia et al., Biometrika, 2019, (). "Multi-resolution localization of causal variants across the genome", Sesia et al., bioRxiv, 2019, ().

News

SNPknock 0.5.0 (10/10/2017)

Initial release

SNPknock 0.5.1 (09/01/2018)

Added a new vignette describing the usage of SNPknock with genotype data.

SNPknock 0.6.0 (02/04/2018)

Changed the functions loading parameter estimates produced by fastPhase. Using "_origchar" file instead of first row of X. Added support for haplotype HMM. Using integer storage for X.

SNPknock 0.7.0 (05/24/2018)

Improved memory efficiency and added support for multithreading. Added more efficient functions for generating knockoff copies of unphased genotypes and phased haplotypes.