Enrichment for Diseases in a Set of Genes

It provides a list of genes associated to diseases (g2d$clean and g2d$complete) based on the following 4 publications (GS2D, Fontaine (2016) , DisGeNET, Pinero (2016) Berto2016, Berto (2016) and PsyGeNET, Sacristan (2015) ). Those lists were combined and manually curated to have matching disease names. When provided a list of gene names, it calculates the disease enrichment of the gene set. The enrichment is calculated using proportion test and Fisher's exact test. Adjusted fdr p-values are returned alongside with p-values combined using the Fisher's method.


Reference manual

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1.0.0 by Deisy Morselli Gysi, 3 years ago

Browse source code at https://github.com/cran/RichR

Authors: Deisy Morselli Gysi and Katja Nowick

Documentation:   PDF Manual  

GPL-2 license

Imports plyr, reshape2, magrittr, stats, metap

See at CRAN