Probability of Detection for Qualitative PCR Methods

This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematical-statistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool 'PROLab' <>. The modelling itself has been described by Uhlig et al. (2015) .


Reference manual

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1.1.0 by Markus Boenn, 9 days ago

Browse source code at

Authors: Markus Boenn (State Office for Consumer Protection Saxony-Anhalt , Germany)

Documentation:   PDF Manual  

GPL-3 license

See at CRAN