An Elastic-Net Regularized Presence-Only Model

Presence-only model with Elastic Net penalty is a regularized generalized linear model training on the presence-absence response. This package provides functions for tuning and fitting the presence-only model. The presence-only model can be used to predict regulatory effects of genetic variants at sequence-level resolution by integrating a large number of epigenetic features and massively parallel reporter assays (MPRAs).


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install.packages("PO.EN")

1.0 by Zikun Yang, 2 months ago


Browse source code at https://github.com/cran/PO.EN


Authors: Zikun Yang [aut, cre, cph] , Chen Wang [ctb] , Iuliana Ionita-Laza [aut, ctb]


Documentation:   PDF Manual  


GPL (>= 2) license


Imports Rcpp, PUlasso, glmnet, pROC

Linking to Rcpp, RcppArmadillo


See at CRAN