Data-Driven qRT-PCR Normalization Using NORMAgene

Enables correction for technical variance in raw quantitative reverse transcription polymerase chain reaction (qRT-PCR) data using the least squares-based NORMAgene data-driven normalization algorithm originally described by Heckmann et al. (2011) . Performs normalization of raw crossing threshold values (CT) and also calculates relative variability metrics that can be used to assess the impact of normalization on variance.


Reference manual

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install.packages("NORMAgene")

0.1.1 by Grant C. O'Connell, 8 months ago


Browse source code at https://github.com/cran/NORMAgene


Authors: Grant C. O'Connell [aut, cre] (ORCID:


Documentation:   PDF Manual  


GPL-3 license


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See at CRAN