A Causal Mediation Method with Methylated Region (MR) as the Mediator

A causal mediation approach under the counterfactual framework to test the significance of total, direct and indirect effects. In this approach, a group of methylated sites from a predefined region are utilized as the mediator, and the functional transformation is used to reduce the possible high dimension in the region-based methylated sites and account for their location information.


Reference manual

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1.0.1 by Qi Yan, 4 months ago

Browse source code at https://github.com/cran/MRmediation

Authors: Qi Yan

Documentation:   PDF Manual  

GPL (>= 2) license

Imports MASS, stats

Depends on fda

See at CRAN