Finding Locally D-optimal optimal designs for some nonlinear and generalized linear models.

this package provides functions for Finding Locally D-optimal designs for Logistic, Negative Binomial, Poisson, Michaelis-Menten, Exponential, Log-Linear, Emax, Richards, Weibull and Inverse Quadratic regression models and also functions for auto-constructing Fisher information matrix and Frechet derivative based on some input variables and without user-interfere.