Analysis of Data from Limiting Dilution Assay (LDA) with or without Cellular Cooperation

Cellular cooperation compromises the established method of calculating clonogenic activity from limiting dilution assay (LDA) data. This tool provides functions that enable robust analysis in presence or absence of cellular cooperation. The implemented method incorporates the same cooperativity module to model the non-linearity associated with cellular cooperation as known from the colony formation assay (Brix et al. (2021) : "Analysis of clonogenic growth in vitro." Nature protocols).


LDAcoop

Repository for CRAN package LDAcoop

Reference manual

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install.packages("LDAcoop")

0.1.2 by Daniel Samaga, 2 years ago


https://github.com/ZytoHMGU/LDAcoop


Report a bug at https://github.com/ZytoHMGU/LDAcoop/issues


Browse source code at https://github.com/cran/LDAcoop


Authors: Daniel Samaga [cre, aut] , Nikko Brix [aut] , Benedek Danko [aut] , Kirsten Lauber [aut] , Horst Zitzelsberger [aut]


Documentation:   PDF Manual  


GPL-3 license


Imports Hmisc

Suggests knitr, rmarkdown, testthat


See at CRAN