Hybrid Analysis of Population and Trio Data with Knockoff Statistics for FDR Control

Identification of putative causal variants in genome-wide association studies using hybrid analysis of both the trio and population designs. The package implements the method in the paper: Yang, Y., Wang, Q., Wang, C., Buxbaum, J., & Ionita-Laza, I. (2024). KnockoffHybrid: A knockoff framework for hybrid analysis of trio and population designs in genome-wide association studies. The American Journal of Human Genetics, in press.


KnockoffTrio

Reference manual

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install.packages("KnockoffHybrid")

1.0.1 by Yi Yang, 2 years ago


Browse source code at https://github.com/cran/KnockoffHybrid


Authors: Yi Yang [aut, cre]


Documentation:   PDF Manual  


GPL-3 license


Imports glmnet, SPAtest


See at CRAN