Adaptive Influence-Based Borrowing for Hybrid Control Trials

Implements the adaptive influence-based borrowing framework proposed by Qinwei Yang, Jingyi Li, Peng Wu, and Shu Yang (2026+) in the paper ``Improving Treatment Effect Estimation in Trials through Adaptive Borrowing of External Controls" for augmenting Randomized Controlled Trials (RCTs) with External Control (EC) data. This package provides a comprehensive workflow to: (1) quantify the comparability of external control samples using influence scores approximated via the influence function of the M-estimator; (2) construct candidate borrowing subsets and select the optimal subset that minimizes the Mean Squared Error (MSE); and (3) calibrate systematic differences in external outcomes using R-learner methods implemented via Ordinary Least Squares or Kernel Ridge Regression.


Reference manual

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install.packages("InfluenceBorrowing")

0.1.0 by Jile Chaoge, 6 months ago


Browse source code at https://github.com/cran/InfluenceBorrowing


Authors: Jile Chaoge [aut, cre] , Peng Wu [aut] , Shu Yang [aut]


Documentation:   PDF Manual  


GPL-3 license


Imports KRLS, stats


See at CRAN