Simulation of Chromosomal Regions Shared by Family Members

Simulation of segments shared identical-by-descent (IBD) by pedigree members. Using sex specific recombination rates along the human genome (Kong et. al (2010) ), phased chromosomes are simulated for all pedigree members, either by unconditional gene dropping or conditional on a specified IBD pattern. Additional functions provide summaries and further analysis of the simulated genomes.


News

NEWS FILE FOR PACKAGE IBDSIM

2017-25-04: Version 0.9-7

  • New function alleleSummary() which greatly facilitates downstream analysis.

  • New function oneLocusIBD() complementing twoLocusIBD().

  • New functions oneLocusJacquard() and twoLocusJacquard().

  • Added file "scr/init.c" to avoid complaints from 'R CMD check' about no calls to 'R_registerRoutines' and 'R_useDynamicSymbols'

2016-26-04: Version 0.9-6

  • New function: twoLocusIBD().

  • Fixed bug in IBDsim() related to pedigree member ordering.

  • Minor improvements and typo corrections.

Reference manual

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install.packages("IBDsim")

0.9-8 by Magnus Dehli Vigeland, 5 months ago


Browse source code at https://github.com/cran/IBDsim


Authors: Magnus Dehli Vigeland


Documentation:   PDF Manual  


GPL (>= 2) license


Imports stats

Depends on paramlink


Depended on by mut.


See at CRAN